Mechano-genomic regulation of coronaviruses and its interplay with ageing
Identifieur interne : 000487 ( 2020/Analysis ); précédent : 000486; suivant : 000488Mechano-genomic regulation of coronaviruses and its interplay with ageing
Auteurs : Caroline Uhler [Suisse] ; G. V. Shivashankar [Suisse]Source :
- Nature Reviews. Molecular Cell Biology [ 1471-0072 ] ; 2020.
Abstract
Coronaviruses employ various nuclear signalling mechanisms for their propagation. Here we link replication of coronaviruses, including SARS-CoV-2, the coronavirus disease 2019 (COVID-19)-causing virus, with cytoskeleton-dependent signalling and 3D genome organization. This link could provide novel insights into the high coronavirus pathogenicity in certain cellular states, particularly those associated with ageing.
Url:
DOI: 10.1038/s41580-020-0242-z
PubMed: 31676888
PubMed Central: 7115351
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000058
- to stream Pmc, to step Curation: 000058
- to stream Pmc, to step Checkpoint: 000183
- to stream Ncbi, to step Merge: 003098
- to stream Ncbi, to step Curation: 003098
- to stream Ncbi, to step Checkpoint: 003098
- to stream Main, to step Merge: 000487
- to stream Main, to step Curation: 000487
- to stream Main, to step Exploration: 000487
- to stream 2020, to step Extraction: 000487
Links to Exploration step
PMC:7115351Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mechano-genomic regulation of coronaviruses and its interplay with ageing</title>
<author><name sortKey="Uhler, Caroline" sort="Uhler, Caroline" uniqKey="Uhler C" first="Caroline" last="Uhler">Caroline Uhler</name>
<affiliation wicri:level="4"><nlm:aff id="Aff1">Department of Biosystems Science & Engineering (D-BSSE), ETH Zurich, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biosystems Science & Engineering (D-BSSE), ETH Zurich</wicri:regionArea>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
</placeName>
<orgName type="university">École polytechnique fédérale de Zurich</orgName>
</affiliation>
</author>
<author><name sortKey="Shivashankar, G V" sort="Shivashankar, G V" uniqKey="Shivashankar G" first="G. V." last="Shivashankar">G. V. Shivashankar</name>
<affiliation wicri:level="4"><nlm:aff id="Aff2">Department of Health Sciences & Technology (D-HEST), ETH Zurich, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Health Sciences & Technology (D-HEST), ETH Zurich</wicri:regionArea>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
</placeName>
<orgName type="university">École polytechnique fédérale de Zurich</orgName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 1090 7501</institution-id>
<institution-id institution-id-type="GRID">grid.5991.4</institution-id>
<institution>Paul Scherrer Institute,</institution>
</institution-wrap>
Villigen, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Villigen</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">31676888</idno>
<idno type="pmc">7115351</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7115351</idno>
<idno type="RBID">PMC:7115351</idno>
<idno type="doi">10.1038/s41580-020-0242-z</idno>
<date when="2020">2020</date>
<idno type="wicri:Area/Pmc/Corpus">000058</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000058</idno>
<idno type="wicri:Area/Pmc/Curation">000058</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000058</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000183</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000183</idno>
<idno type="wicri:Area/Ncbi/Merge">003098</idno>
<idno type="wicri:Area/Ncbi/Curation">003098</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">003098</idno>
<idno type="wicri:doubleKey">1471-0072:2020:Uhler C:mechano:genomic:regulation</idno>
<idno type="wicri:Area/Main/Merge">000487</idno>
<idno type="wicri:Area/Main/Curation">000487</idno>
<idno type="wicri:Area/Main/Exploration">000487</idno>
<idno type="wicri:Area/2020/Extraction">000487</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Mechano-genomic regulation of coronaviruses and its interplay with ageing</title>
<author><name sortKey="Uhler, Caroline" sort="Uhler, Caroline" uniqKey="Uhler C" first="Caroline" last="Uhler">Caroline Uhler</name>
<affiliation wicri:level="4"><nlm:aff id="Aff1">Department of Biosystems Science & Engineering (D-BSSE), ETH Zurich, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biosystems Science & Engineering (D-BSSE), ETH Zurich</wicri:regionArea>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
</placeName>
<orgName type="university">École polytechnique fédérale de Zurich</orgName>
</affiliation>
</author>
<author><name sortKey="Shivashankar, G V" sort="Shivashankar, G V" uniqKey="Shivashankar G" first="G. V." last="Shivashankar">G. V. Shivashankar</name>
<affiliation wicri:level="4"><nlm:aff id="Aff2">Department of Health Sciences & Technology (D-HEST), ETH Zurich, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Health Sciences & Technology (D-HEST), ETH Zurich</wicri:regionArea>
<placeName><settlement type="city">Zurich</settlement>
<region nuts="3" type="region">Canton de Zurich</region>
</placeName>
<orgName type="university">École polytechnique fédérale de Zurich</orgName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 1090 7501</institution-id>
<institution-id institution-id-type="GRID">grid.5991.4</institution-id>
<institution>Paul Scherrer Institute,</institution>
</institution-wrap>
Villigen, Switzerland</nlm:aff>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Villigen</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Nature Reviews. Molecular Cell Biology</title>
<idno type="ISSN">1471-0072</idno>
<idno type="eISSN">1471-0080</idno>
<imprint><date when="2020">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="Par1">Coronaviruses employ various nuclear signalling mechanisms for their propagation. Here we link replication of coronaviruses, including SARS-CoV-2, the coronavirus disease 2019 (COVID-19)-causing virus, with cytoskeleton-dependent signalling and 3D genome organization. This link could provide novel insights into the high coronavirus pathogenicity in certain cellular states, particularly those associated with ageing.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="De Wit, E" uniqKey="De Wit E">E de Wit</name>
</author>
<author><name sortKey="Van Doremalen, N" uniqKey="Van Doremalen N">N van Doremalen</name>
</author>
<author><name sortKey="Falzarano, D" uniqKey="Falzarano D">D Falzarano</name>
</author>
<author><name sortKey="Munster, Vj" uniqKey="Munster V">VJ Munster</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Poppe, M" uniqKey="Poppe M">M Poppe</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Uhler, C" uniqKey="Uhler C">C Uhler</name>
</author>
<author><name sortKey="Shivashankar, Gv" uniqKey="Shivashankar G">GV Shivashankar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Discher, De" uniqKey="Discher D">DE Discher</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jain, N" uniqKey="Jain N">N Jain</name>
</author>
<author><name sortKey="Iyer, Kv" uniqKey="Iyer K">KV Iyer</name>
</author>
<author><name sortKey="Kumar, A" uniqKey="Kumar A">A Kumar</name>
</author>
<author><name sortKey="Shivashankar, Gv" uniqKey="Shivashankar G">GV Shivashankar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name>
</author>
<author><name sortKey="Nagarajan, M" uniqKey="Nagarajan M">M Nagarajan</name>
</author>
<author><name sortKey="Uhler, C" uniqKey="Uhler C">C Uhler</name>
</author>
<author><name sortKey="Shivashankar, Gv" uniqKey="Shivashankar G">GV Shivashankar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Damodaran, K" uniqKey="Damodaran K">K Damodaran</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mitra, A" uniqKey="Mitra A">A Mitra</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Uhler, C" uniqKey="Uhler C">C Uhler</name>
</author>
<author><name sortKey="Shivashankar, Gv" uniqKey="Shivashankar G">GV Shivashankar</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>Suisse</li>
</country>
<region><li>Canton de Zurich</li>
</region>
<settlement><li>Zurich</li>
</settlement>
<orgName><li>École polytechnique fédérale de Zurich</li>
</orgName>
</list>
<tree><country name="Suisse"><region name="Canton de Zurich"><name sortKey="Uhler, Caroline" sort="Uhler, Caroline" uniqKey="Uhler C" first="Caroline" last="Uhler">Caroline Uhler</name>
</region>
<name sortKey="Shivashankar, G V" sort="Shivashankar, G V" uniqKey="Shivashankar G" first="G. V." last="Shivashankar">G. V. Shivashankar</name>
<name sortKey="Shivashankar, G V" sort="Shivashankar, G V" uniqKey="Shivashankar G" first="G. V." last="Shivashankar">G. V. Shivashankar</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/2020/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000487 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/2020/Analysis/biblio.hfd -nk 000487 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= 2020 |étape= Analysis |type= RBID |clé= PMC:7115351 |texte= Mechano-genomic regulation of coronaviruses and its interplay with ageing }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/2020/Analysis/RBID.i -Sk "pubmed:31676888" \ | HfdSelect -Kh $EXPLOR_AREA/Data/2020/Analysis/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
This area was generated with Dilib version V0.6.33. |